abstract：:Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is standard of care for locally advanced esophageal cancer in many countries. After nCRT up to one third of all patients have a pathologically complete response in the resection specimen, posing an ethical imperative to reconsider the necessity of standard surge...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Noordman BJ,Wijnhoven BPL,Lagarde SM,Biermann K,van der Gaast A,Spaander MCW,Valkema R,van Lanschot JJB

更新日期：2017-12-01 00:00:00

abstract：:The effect of endoscopic submucosal dissection (ESD) on esophageal motility remains unknown. Therefore, the aim of this study is to elucidate changes in esophageal motility after ESD along with the cause of dysphagia using high-resolution manometry (HRM). This is a before-and-after trial of the effect of ESD on the es...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Takahashi K,Sato Y,Takeuchi M,Sato H,Nakajima N,Ikarashi S,Hayashi K,Mizuno KI,Honda Y,Hashimoto S,Yokoyama J,Terai S

更新日期：2017-11-01 00:00:00

abstract：:Unconsciously caustic ingestion is one of the most common causes of serious esophageal strictures in children. The aim of this study is to determine the efficiency of polaprezinc in preventing stricture formation after corrosive esophageal burns (CEB); this was the first time it has been used to treat experimental CEB...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Ozbayoglu A,Sonmez K,Karabulut R,Turkyilmaz Z,Poyraz A,Gulbahar O,Basaklar AC

更新日期：2017-11-01 00:00:00

abstract：:This study assessed the clinical value of CYFRA 21-1 in comparison with squamous cell carcinoma antigen (SCC-Ag), carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) in patients with esophageal squamous cell carcinoma. In 112 primary cancer patients, the diagnostic sensitivity of CYFRA 21-1 (33.9%) ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Nakamura T,Ide H,Eguchi R,Hayashi K,Takasaki K,Watanabe S

更新日期：2017-11-01 00:00:00

abstract：:The increasing incidence of adenocarcinoma of the lower esophagus and cardia arising in Barrett's metaplastic epithelium continues to be of great concern because medical and surgical efforts to reverse the process have been disappointing. A potential answer to the problem is removal of the metaplastic epithelium. Mode...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bremner CG,Demeester TR

更新日期：2017-11-01 00:00:00

abstract：:The objective of this study is the feasibility of sequential endoscopic and endosonographic measurement of locoregional tumor load for the prediction of tumor recurrence in patients after neoadjuvant or definitive chemoradiotherapy, treated in curative intent for locally advanced esophageal carcinoma. In 67 patients w...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bohle W,Kasper M,Zoller WG

更新日期：2017-10-01 00:00:00

abstract：:Survival of patients with esophageal adenocarcinoma remains poor and individual differences in prognosis remain unexplained. This study investigated whether gene mutations can explain why patients with high-risk (pT3-4, pN+) esophageal adenocarcinoma survive past 5 years after esophagectomy. Six long-term survivors (L...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Visser E,Franken IA,Brosens LAA,de Leng WWJ,Strengman E,Offerhaus JA,Ruurda JP,van Hillegersberg R

更新日期：2017-09-01 00:00:00

abstract：:Recurrent tracheoesophageal fistula (rTEF) is a complex complication after the repair of esophageal atresia (EA) and remains a challenge because of difficulties in preoperative management and the substantial rates of mortality and morbidity after reoperation. By reviewing a single institution's experience in the manag...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Wang J,Zhang M,Pan W,Wu W,Yan W,Cai W

更新日期：2017-09-01 00:00:00

abstract：:We performed a systematic review of epidemiological, diagnostic, and therapeutic outcomes of esophageal perforations. A systematic review was performed in PubMed database using the key-phrase 'esophageal perforation'. All studies regarding acute esophageal perforations were reviewed and parameters of epidemiology, dia...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sdralis EIK,Petousis S,Rashid F,Lorenzi B,Charalabopoulos A

更新日期：2017-08-01 00:00:00

abstract：:The rarity of primary small cell carcinoma of the esophagus (PSCE) has limited the clinical feature and survival analysis with large sample size. Tissue chromogranin A (CgA) protein expression has been reported to be a useful biomarker for diagnosing PSCE. Interestingly, recent studies have indicated tissue CgA as a s...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Ku JW,Zhang DY,Song X,Li XM,Zhao XK,Lv S,Hu SJ,Cheng R,Zhou FY,Wu HF,Wang LD

更新日期：2017-08-01 00:00:00

abstract：:Routine esophageal manometry for surgical planning before laparoscopic paraesophageal hernia (PEH) has been advocated in an effort to reduce the likelihood of postoperative dysphagia. The purpose of this study is to investigate whether omitting routine preoperative esophageal manometry is associated with a change in t...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zevin B,Jones EL,Martin Del Campo SE,Perry KA

更新日期：2017-07-01 00:00:00

abstract：:Nowadays esophageal squamous cell carcinoma (ESCC) is primarily treated by a comprehensive approach combining surgical resection and neoadjuvant chemo- or radiotherapy. However, ESCC is resistant to radiation therapy, resulting in its invasion, infiltration, and metastasis. It usually has rapidly progressed and has a ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Qian X,Tan C,Yang B,Wang F,Ge Y,Guan Z,Cai J

更新日期：2017-06-01 00:00:00

abstract：:Achalasia may present in a non-advanced or an advanced (end stage) stage based on the degree of esophageal dilatation. Manometric parameters and esophageal caliber may be prognostic for the outcome of treatment. The correlation between manometry and disease stage has not been yet fully studied. This study aims to desc...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Menezes MA,Andolfi C,Herbella FA,Patti MG

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Patient-reported outcome (PRO) measures are commonly used to capture patient experience with dysphagia and to evaluate treatment effectiveness. Inappropriate application can lead to distorted results in clinical studies. A systematic review of the literature on dysphagia-related PRO measures was performed to ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Patel DA,Sharda R,Hovis KL,Nichols EE,Sathe N,Penson DF,Feurer ID,McPheeters ML,Vaezi MF,Francis DO

更新日期：2017-05-01 00:00:00

abstract：:The aim of this study is to compare endoscopic stent suture fixation with endoscopic clip attachment or the use of partially covered stents (PCS) regarding their capability to prevent stent migration during prolonged dilatation in achalasia. Large-diameter self-expanding metal stents (30 mm × 80 mm) were placed across...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Rieder E,Asari R,Paireder M,Lenglinger J,Schoppmann SF

更新日期：2017-04-01 00:00:00

abstract：:Day-case esophageal surgery has been demonstrated to be safe in small prospective cohorts and only for laparoscopic fundoplication. The aims of this study are to assess the feasibility and safety of a large series of esophageal day-case surgeries, including laparoscopic Nissen fundoplication (LNF), Zenker diverticulec...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Desbeaux A,Gronnier C,Piessen G,Vanderbeken M,Ruolt N,Triboulet JP,Mariette C

更新日期：2017-04-01 00:00:00

abstract：:Barrett's esophagus is a well-recognized risk factor for esophageal adenocarcinoma. The natural history of Barrett's esophagus classified as ‘indefinite for dysplasia’ (IND) is poorly characterized. The aim of this study is to characterize the natural history of IND by determining the rate of neoplastic progression an...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Ma M,Shroff S,Feldman M,DeMarshall M,Price C,Tierney A,Falk GW

更新日期：2017-03-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is a common disorder of the upper gastrointestinal tract which is typically characterized by heartburn and acid regurgitation. These symptoms are widespread in the community and range from 2.5% to more than 25%. Economic analyses showed an increase in direct and indirect costs re...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Savarino E,de Bortoli N,De Cassan C,Della Coletta M,Bartolo O,Furnari M,Ottonello A,Marabotto E,Bodini G,Savarino V

更新日期：2017-02-01 00:00:00

abstract：:Self-expanding metal stents (SEMS) are the treatment of choice for advanced esophageal cancers. Literature is scarce on risk factors predictors for adverse events after SEMS placement. Assess risk factors for adverse events after SEMS placement in advanced esophageal cancer and evaluate survival after SEMS placement. ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Rodrigues-Pinto E,Pereira P,Coelho R,Andrade P,Ribeiro A,Lopes S,Moutinho-Ribeiro P,Macedo G

更新日期：2017-02-01 00:00:00

abstract：:The incidence of esophageal cancer has risen dramatically in the Western world. Although surgical resection of esophageal tumors is considered the cornerstone of curative approaches in localized esophageal cancer, approximately 40% of patients who undergo chemoradiation followed by surgery will experience a recurrence...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Mikhail S,Wei L,Salem ME,Bekaii-Saab T

更新日期：2017-02-01 00:00:00

abstract：:Esophageal squamous cell carcinoma (ESCC) is one of the most frequently diagnosed cancers in China, but the etiology and mode of carcinogenesis of this disease remain poorly understood. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), as a negative regulator of Akt/mTOR pathway, frequently mutates or is...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lu Z,Wang J,Zheng Y,Yang S,Liu M,Chen X,Wang C,Hou G

更新日期：2017-02-01 00:00:00

abstract：:The placement of metal stents is often used as a palliative treatment for malignant esophageal stenosis. We designed a novel stent that has been used clinically since 2011, and we therefore performed a retrospective study to compare the therapeutic effects of this novel metal stent to a conventional partially covered ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Chen H,Ni Z,Jing D,He L,Qiao L,Liu L,Wei X,Jiang M,Tang S,Xu H

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND AIMS:There has been a recent increase in the incidence of oropharyngeal cancer (OPC) associated with high-risk human papilloma virus (HPV) infection. We investigated the incidence of esophageal papilloma and the presence of high-risk HPV infection. METHODS:This is a cross-sectional study conducted at a ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Pantham G,Ganesan S,Einstadter D,Jin G,Weinberg A,Fass R

更新日期：2017-01-01 00:00:00

abstract：:Obesity increases the risk of gastroesophageal reflux disease (GERD). The majority of the reflux attacks occur postprandially. The influence of the speed of food intake on gastroesophageal reflux events is unclear in obese patients. To determine the influence of the speed of food intake on intraesophageal reflux event...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bor S,Erdogan A,Bayrakci B,Yildirim E,Vardar R

更新日期：2017-01-01 00:00:00

abstract：:Esophageal cancer is the sixth leading cause of cancer-associated death worldwide. Phospholipase C epsilon 1 (PLCE1) gene was found to be associated with the risk of esophageal squamous cell carcinoma (ESCC) by three large-scale genome-wide association studies (GWAS) in Chinese populations. To evaluate the association...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Qu Y,Zhang S,Cui L,Wang K,Song C,Wang P,Zhang J,Dai L

更新日期：2017-01-01 00:00:00

abstract：:The impact of body weight on outcomes after robotic-assisted esophageal surgery for cancer has not been studied. We examined the short-term operative outcomes in patients according to their body mass index following robotic-assisted Ivor-Lewis esophagectomy at a high-volume tertiary-care referral cancer center and eva...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Salem AI,Thau MR,Strom TJ,Abbott AM,Saeed N,Almhanna K,Hoffe SE,Shridhar R,Karl RC,Meredith KL

更新日期：2017-01-01 00:00:00

abstract：:We conducted a retrospective analysis to assess the toxicity and long-term survival of esophageal squamous cell carcinoma patients treated with three-dimensional conformal radiotherapy (3DCRT) or intensity-modulated radiotherapy (IMRT) versus conventional two-dimensional radiotherapy (2DRT). All data in the present st...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Deng JY,Wang C,Shi XH,Jiang GL,Wang Y,Liu Y,Zhao KL

更新日期：2016-11-01 00:00:00

abstract：:We report analytic and consensus processes that produced recommendations for neoadjuvant pathologic stage groups (ypTNM) of esophageal and esophagogastric junction cancer for the AJCC/UICC cancer staging manuals, 8th edition. The Worldwide Esophageal Cancer Collaboration provided data for 22,654 patients with epitheli...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Rice TW,Ishwaran H,Kelsen DP,Hofstetter WL,Apperson-Hansen C,Blackstone EH,Worldwide Esophageal Cancer Collaboration Investigators.

更新日期：2016-11-01 00:00:00

abstract：:Non-Hodgkin lymphoma involving the esophagus is very rare. Only a few cases have been reported in the English literature to date, and it accounts for less than 1% of all cases of gastrointestinal lymphoma. As this malignancy manifests as a submucosal tumor, pathological diagnosis by using a simple endoscopic biopsy al...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lee DS,Ahn YC,Eom DW,Lee SJ

更新日期：2016-10-01 00:00:00

abstract：:Esophageal squamous cell carcinoma (ESCC) is one of the most malignant cancers in Japan. Anticancer chemotherapy has been useful for ESCC treatment. However, therapeutic options are limited. Recently, bisphosphonates (BPs), which are osteoporosis drugs, have shown anticancer effects in several cancer cell lines, but t...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Minegaki T,Fukushima S,Morioka C,Takanashi H,Uno J,Tsuji S,Yamamoto S,Watanabe A,Tsujimoto M,Nishiguchi K

更新日期：2016-08-01 00:00:00

abstract：:We present the first report on peroral endoscopic myotomy (POEM) in the treatment of jackhammer esophagus. A 34-year-old female patient was newly diagnosed with a jackhammer esophagus. After failure of medical treatment, the patient underwent POEM procedure for myotomy of the spastic segment. Postoperatively, a mild e...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Kandulski A,Fuchs KH,Weigt J,Malfertheiner P

更新日期：2016-08-01 00:00:00

abstract：:Achalasia is a primary esophageal motility disorder. Unlike diffuse esophageal spasm, it has not previously been described in association with hereditary sensory and motor neuropathy (HSMN). An 18-year-old-male with HSMN with sensorineural deafness presented with a 2-day history of dysphagia to solids and liquids. Ach...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Asthana AK,Lubel JS,Kohn GP

更新日期：2016-08-01 00:00:00

abstract：:Transthoracic esophagectomy (TTE) is believed to have advantages for mediastinal lymphadenectomy in the treatment of resectable esophageal cancer despite its association with a greater incidence of pulmonary complications and postoperative mortality. Transhiatal esophagectomy is regarded as less invasive, though insuf...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Mori K,Yamagata Y,Aikou S,Nishida M,Kiyokawa T,Yagi K,Yamashita H,Nomura S,Seto Y

更新日期：2016-07-01 00:00:00

abstract：:This prospective population-based study was designed to evaluate treatment choices in patients with new manometrically diagnosed achalasia and their outcomes. Patients referred to the esophageal function laboratory were enrolled after a new manometric diagnosis of achalasia. Patients completed an initial achalasia sym...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Yeung JC,Finley C,Hanna WC,Miller L,Ferri L,Urbach DR,Darling GE

更新日期：2016-07-01 00:00:00

abstract：:A wide variety of pieces of evidence has suggested that obesity is associated with a significant increase in the risk for gastroesophageal reflux disease (GERD) symptoms and its complications. The aim of this study was to evaluate the effect of weight loss on reflux symptoms in overweight/obese patients with proven GE...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： de Bortoli N,Guidi G,Martinucci I,Savarino E,Imam H,Bertani L,Russo S,Franchi R,Macchia L,Furnari M,Ceccarelli L,Savarino V,Marchi S

更新日期：2016-02-01 00:00:00

abstract：:Long-term survival after esophagectomy is improving, and hence, quality of life (QOL) of these patients has become a priority. There has been extensive debate regarding the optimal site of surgical anastomosis (cervical or intrathoracic). We aimed to evaluate the impact of anastomotic site on long-term QOL postesophag...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Wormald JC,Bennett J,van Leuven M,Lewis MP

更新日期：2016-01-01 00:00:00

abstract：:High-resolution manometry identifies three subtypes of achalasia. However, type 3 differs from classic achalasia. Although opiates affect esophageal motility, opiate use and achalasia have not been studied. Patients with a new diagnosis of achalasia at Mayo Clinic Rochester between June 1, 2012 and January 3, 2014 wer...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Ravi K,Murray JA,Geno DM,Katzka DA

更新日期：2016-01-01 00:00:00

abstract：:In the UK, the standard of care for esophageal cancer has generally combined surgery with neoadjuvant chemotherapy, with definitive chemoradiotherapy (dCRT) being reserved for certain subgroups. Chemoradiotherapy followed by surgery (trimodality therapy) has not been widely adopted. The outcomes of patients undergoing...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hategan M,Cook N,Prewett S,Hindmarsh A,Qian W,Gilligan D

更新日期：2015-10-01 00:00:00

abstract：:The aim of this paper is to investigate the diagnostic value of histopathologic score and the dilated intercellular space (DIS) in patients with gastroesophageal reflux disease (GERD) and functional heartburn (FH). Participants with GERD symptoms including reflux esophagitis, non-erosive reflux disease (NERD), Barrett...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Cui R,Zhang H,Zhou L,Lu J,Xue Y,Wang Y,Yan X,Lin L,Lin S

更新日期：2015-08-01 00:00:00

abstract：:Esophageal cancer recurrence rates after esophagectomy are high, and locally recurrent or distant metastatic disease has poor prognosis. Management is limited to palliative chemotherapy and symptomatic interventions. We report our experience of four patients who have undergone successful liver resection for metastases...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Huddy JR,Thomas RL,Worthington TR,Karanjia ND

更新日期：2015-07-01 00:00:00